NEW TECHNIQUES AND METHODS IN THE STUDY OF THE INVASION, CELL MIGRATION AND MMPS ACTIVITY IN VITRO AND IN ANIMAL MODELS

New techniques and methods in the study of the invasion, cell migration and MMPs activity in vitro and in animal models

Background & Objective: Cancer metastasis is the primary cause of cancer morbidity and mortality, it accounts for about 90% of cancer deaths.Cancer treatment has improved significantly, due to early detection and inhibition of cancer growth.The ability to invade and migrate is important in malignant tumor cells.The study of cell migration is valuab

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FORMATION OF THE HYPOTHESIS ABOUT THE EAST SLAVIC CITY - THE ADMINISTRATIVE CENTER IN THE RUSSIAN HISTORICAL KNOWLEDGE OF THE 18TH CENTURY

In Russian historiography, for more than a century, there have been disputes about the possible reasons for the origin of East Slavic / Old Russian cities.Today, several hypotheses coexist: 1) cities are products of state power, 2) their emergence was influenced by the trade and craft factor, 3) the needs of defense influenced the formation of town

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